Open AccessApplication of chromosomal microarray for evaluation of idiopathic short stature in Asian Indian children: A pilot study
Author(s) -
Hema Singh,
Pradeep Tiwari,
Vijay Kumar Bhavi,
Praveen Chaudhary,
Prashanth Suravajhala,
M. Krishna Mohan,
Sandeep Kumar Mathur
Publication year - 2018
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/ijem.ijem_202_17
Subject(s) - short stature , idiopathic short stature , haploinsufficiency , medicine , copy number variation , turner syndrome , microarray , genetics , pediatrics , bioinformatics , phenotype , gene , biology , genome , growth hormone , hormone , gene expression
Human height is a classic polygenic trait and currently available data explains only 10% of the phenotypic variation in height. Almost 60%-80% of the children coming to pediatric and endocrinology outpatient department for the evaluation of short stature are still labeled as idiopathic.