Open AccessComparative evaluation of safety and efficacy of glimepiride and sitagliptin in combination with metformin in patients with type 2 diabetes mellitus: Indian multicentric randomized trial - START Study
Author(s) -
T V Devarajan,
Satchi Venkataraman,
Narayanan Kandasamy,
Abraham Oomman,
Hari Kishan Boorugu,
Stalin Karuppiah,
Dushyant Balat
Publication year - 2017
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/ijem.ijem_176_17
Subject(s) - glimepiride , sitagliptin , medicine , metformin , glycemic , type 2 diabetes mellitus , tolerability , type 2 diabetes , clinical endpoint , postprandial , glycemic index , gastroenterology , endocrinology , diabetes mellitus , randomized controlled trial , pharmacology , adverse effect
Modern sulfonylureas like glimepiride offer effective glycemic control with extrapancreatic benefits and good tolerability. The objective of the present study was to evaluate and compare safety and efficacy of glimepiride and sitagliptin in combination with metformin in patients with type 2 diabetes mellitus (T2DM).