Open AccessExocrine dysfunction correlates with endocrinal impairment of pancreas in Type 2 diabetes mellitus
Author(s) -
Hitesh Kumar,
H. Basavana Gowdappa,
Tejashwi Hosmani,
Tejashri Urs
Publication year - 2018
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/ijem.ijem_139_17
Subject(s) - medicine , endocrine system , glycated hemoglobin , exocrine pancreatic insufficiency , pancreas , diabetes mellitus , gastroenterology , type 2 diabetes mellitus , endocrinology , biomarker , type 2 diabetes , hormone , biochemistry , chemistry
Diabetes mellitus (DM) is a chronic abnormal metabolic condition, which manifests elevated blood sugar level over a prolonged period. The pancreatic endocrine system generally gets affected during diabetes, but often abnormal exocrine functions are also manifested due to its proximity to the endocrine system. Fecal elastase-1 (FE-1) is found to be an ideal biomarker to reflect the exocrine insufficiency of the pancreas.