Open AccessFeasibility of bisphosphonate therapy in an Indian pediatric patient of fibrodysplasia ossificans progressiva
Author(s) -
Inderpal Singh Kochar,
Aashish Sethi,
Smita Ramachandran
Publication year - 2019
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/ijabmr.ijabmr_52_18
Subject(s) - fibrodysplasia ossificans progressiva , medicine , myositis ossificans , osteogenesis imperfecta , bisphosphonate , surgery , pediatrics , dermatology , osteoporosis , ossification , pathology
Fibrodysplasia ossificans progressiva, also known as myositis ossificans progressiva, is a rare autosomal dominant disorder (1 in 2 million). It produces a catastrophic and crippling illness in young people for which there is no effective treatment. This case report presents a case of 7-year-old child misdiagnosed as osteogenesis imperfecta admitted with severe disability and pain. He was diagnosed by clinical and radiological methods, treated with bisphosphonates for pain relief along with calcium and Vitamin D, and followed till 4 years.