Open AccessRole of immunophenotypes in carcinoma breast
Author(s) -
Samarth Shukla,
Sourya Acharya,
Sunita Vagha,
Pratibha Dawande,
Ankita Tamhane
Publication year - 2018
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/ijabmr.ijabmr_331_17
Subject(s) - breast cancer , medicine , breast carcinoma , histopathology , mastectomy , grading (engineering) , oncology , lymph node , pathology , h&e stain , immunohistochemistry , cancer , biology , ecology
Nottingham's modification of Bloom-Richardson histopathological grading system (NGS) for carcinoma breast is a time-tested prognostic indicator; however, of lately, breast cancer has been evaluated through molecular techniques, particularly assessing the gene expression profiling and establishing molecular or immunophenotypes. The present-day utility of NGS needs to be reassessed with the modern predictive markers, this may help refine breast cancer classification specifically to help improve the treatment protocol.