Open AccessComparative evaluation of oral melatonin and oral clonidine for the attenuation of haemodynamic response to laryngoscopy and tracheal intubation—A prospective randomised double blind study
Author(s) -
S. K. Choudhary,
Sandeep Sharma,
Indira Kumari,
Swathi Kalluraya,
Khemraj Meena,
Tanuj Dave
Publication year - 2020
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/ija.ija_76_20
Subject(s) - anesthesia , laryngoscopy , medicine , intubation , clonidine , sedation , hemodynamics , blood pressure , heart rate , general anaesthesia , tracheal intubation , mean arterial pressure
Laryngoscopy and endotracheal intubation cause significant derangement of the haemodynamic parameters proving detrimental for some patients. Clonidine, an α-2 adrenoreceptor agonist, and melatonin, the pineal hormone, have been used for the attenuation of these haemodynamic responses. This study was designed to evaluate the effect of oral melatonin and clonidine in attenuating the haemodynamic responses to laryngoscopy and intubation.