
Comparison of efficacy of palonosetron-dexamethasone combination with palonosetron or dexamethasone alone for prophylaxis against post-operative nausea and vomiting in patients undergoing laparoscopic cholecystectomy
Author(s) -
Arindam Chatterjee,
Sandeep Sahu,
Mekhala Paul,
Tanya Singh,
Saurabh Singh,
Prabhaker Mishra
Publication year - 2017
Publication title -
indian journal of anaesthesia/indian journal of anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.645
H-Index - 30
eISSN - 0976-2817
pISSN - 0019-5049
DOI - 10.4103/ija.ija_317_17
Subject(s) - palonosetron , medicine , dexamethasone , antiemetic , nausea , anesthesia , postoperative nausea and vomiting , vomiting , surgery
Post-operative nausea and vomiting (PONV) is highly distressing and unpleasant symptom. Dexamethasone and palonosetron are effective antiemetics with minimal side effect profile. This study compares the efficacy of palonosetron or dexamethasone alone and their combination (palonosetron plus dexamethasone) for prevention of PONV after laparoscopic cholecystectomy.