Open AccessSkin barrier function defect - A marker of recalcitrant tinea infections
Author(s) -
Puneet Bhargava,
Shivi Nijhawan,
Heena Singdia,
Taniya Mehta
Publication year - 2020
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/idoj.idoj_434_19
Subject(s) - medicine , transepidermal water loss , dermatology , prospective cohort study , pathology , stratum corneum
Recently, there has been an increase in the number of chronic, recurrent, and recalcitrant dermatophytosis. Many factors implicated are barrier defects, aberrant host immune response, application of steroids or other irrational combination creams, transmission within family, occlusive clothing, poor hygienic conditions, poor compliance, drug resistance and virulence of the infecting strain. Transepidermal water loss (TEWL) is an important index in accessing the barrier function of skin.