Open AccessA pilot analysis of morphometric assessment of itraconazole brands using dermoscopy and its relevance in the current scenario
Author(s) -
Kabir Sardana,
Ananta Khurana,
Ajeet Singh,
R. K. Gautam
Publication year - 2018
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/idoj.idoj_339_17
Subject(s) - pellet , innovator , pellets , medicine , itraconazole , capsule , sample size determination , bioavailability , statistics , mathematics , materials science , computer science , dermatology , composite material , pharmacology , antifungal , botany , intellectual property , biology , operating system
Itraconazole (ITZ) is widely used for cutaneous and systemic mycoses. Its bioavailability is inconsistent and shows interindividual variations. The quality of ITZ pellets is an important factor determining its absorption profile and thereby the therapeutic effect. Analysis of morphometric characteristics is a surrogate method to determine the same. Pellet number and size are the most important parameters in this regard.