Open AccessImatinib-induced IgA pemphigus: Subcorneal pustular dermatosis type
Author(s) -
Aradhana Bela Sood,
Preema Sinha,
Deep Kumar Raman,
Anwita Sinha
Publication year - 2018
Publication title -
indian dermatology online journal
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/idoj.idoj_331_17
Subject(s) - medicine , dapsone , pemphigus , imatinib , dermatology , imatinib mesylate , myeloid leukemia , prednisolone , immunology , gastroenterology
Imatinib mesylate, a tyrosine kinase inhibitor, is commonly used in the treatment of chronic myeloid leukemia. IgA pemphigus is a rare bullous dermatosis caused by IgA autoantibodies. Clinical manifestations include localized or generalized itchy blisters and pustules. Drug-induced IgA pemphigus has been rarely reported in the literature till date. Here, we report one such rare case caused by imatinib which responded poorly to oral prednisolone but showed excellent response to tablet dapsone.