Open AccessUse of transient elastography in detection of liver fibrosis in psoriasis patients – A cross- sectional study
Author(s) -
Shekhar Neema,
Debabrata Banerjee,
S. Radhakrishnan,
Biju Vasudevan,
Preema Sinha,
Bhavni Oberoi
Publication year - 2020
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/idoj.idoj_312_19
Subject(s) - medicine , transient elastography , psoriasis , metabolic syndrome , liver biopsy , methotrexate , gastroenterology , waist , fibrosis , biopsy , diabetes mellitus , dermatology , obesity , endocrinology
The risk of liver damage in psoriasis increases with increase in cumulative dose of methotrexate and guidelines suggest use of liver biopsy for risk mitigation. Recently, transient elastography (TE) has been used for detection of liver fibrosis. Most studies for TE are in hepatitis B and C patients. However, psoriasis patients have risk factors like metabolic syndrome which predisposes them to increased risk of liver damage due to methotrexate. This underlying liver disease may change the TE values in patients with psoriasis. The aim of this study is to determine utility of transient elastography in detection of liver fibrosis in patients with psoriasis.