Open AccessEGFR inhibitors-related panniculitis: A new side effect
Author(s) -
Sofia Lopes,
Aogueira,
Joana Pardal,
Filomena Azevedo
Publication year - 2019
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/idoj.idoj_273_18
Subject(s) - medicine , epidermal growth factor receptor , panniculitis , dermatology , egfr inhibitors , drug , pharmacology , receptor
Epidermal growth factor receptor (EGFR) inhibitors are widely used in the treatment of advanced malignancies, and their skin toxicity is frequent and well recognized in the literature. We report the case of a 69-year-old patient with a history of adenocarcinoma of the lung treated with several EGFR inhibitors and the development of skin lesions compatible with panniculitis. The reproducibility of the lesions with different inhibitors reinforces the causal relationship with the drug, representing the first report in the literature of this side effect.