Open AccessExpression of vascular endothelial growth factor and microvessel density in psoriatic skin lesions
Author(s) -
Priya T Rajan,
T N Suresh,
T S Rajashekar
Publication year - 2018
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/idoj.idoj_147_17
Subject(s) - medicine , psoriasis , cd34 , pathology , papillary dermis , vascular endothelial growth factor , immunohistochemistry , microvessel , angiogenesis , dermis , pathogenesis , vegf receptors , dermatology , biology , genetics , stem cell
Psoriasis is a common chronic and immune-mediated skin disorder having a significant impact on the patient's quality of life. An analysis of the role of angiogenic vascular endothelial growth factor (VEGF) expression and microvessel density in psoriatic skin lesions may help in better understanding of the disease pathogenesis. The aim of this study was to examine the expression of vascular endothelial growth factor (VEGF) and microvessel density using CD34 antibodies in psoriatic skin lesions by immunohistochemical examination using normal skin of healthy individuals as controls.