Open AccessComplement receptor 1 (CR1)/ CD35+ expression analysis of salivary neutrophils on Streptococcus mutans phagocytosis
Author(s) -
Muhammad Luthfi,
Retno Indrawati,
Aqsa Sjuhada Oki,
Muhaimin Rifa’i
Publication year - 2019
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/ccd.ccd_900_18
Subject(s) - streptococcus mutans , phagocytosis , saliva , complement receptor , microbiology and biotechnology , receptor , complement system , innate immune system , immunology , medicine , biology , immune system , bacteria , genetics
Severe early childhood caries (S-ECC) is a form of dental caries which is very destructive in early childhood since involving several teeth, include the maxillary anterior teeth. Streptococcus mutans (S. mutans) play an etiological integral role of ECC so that S. mutans are considered as the predictor of dental caries. The neutrophil is a key component of the rst line of defense against microbial invasion. The essential function of neutrophil is to kill pathogenic microbes through a phagocytosis process which is mediated by Complement Receptor 1 (CR1)/ (CD35 + ).