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Severe early childhood caries (S-ECC) is a form of dental caries which is very destructive in early childhood since involving several teeth, include the maxillary anterior teeth. Streptococcus mutans (S. mutans) play an etiological integral role of ECC so that S. mutans are considered as the predictor of dental caries. The neutrophil is a key component of the rst line of defense against microbial invasion. The essential function of neutrophil is to kill pathogenic microbes through a phagocytosis process which is mediated by Complement Receptor 1 (CR1)/ (CD35 + ).

Complement receptor 1 (CR1)/ CD35+ expression analysis of salivary neutrophils on Streptococcus mutans phagocytosis

Complement receptor 1 (CR1)/ CD35⁺ expression analysis of salivary neutrophils on Streptococcus mutans phagocytosis