Open AccessCytotoxicity evaluation of combination irrigant regimens with MTAD on two different cell lines
Author(s) -
Manikandan Ravinanthanan,
Mithra N Hegde,
Veena Shetty,
Suchetha Kumari
Publication year - 2018
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/ccd.ccd_854_17
Subject(s) - trypan blue , cytotoxicity , viability assay , chemistry , hela , chlorhexidine , pulmonary surfactant , sodium hypochlorite , sulforhodamine b , cetrimide , mtt assay , pharmacology , cell , medicine , biochemistry , dentistry , in vitro , organic chemistry
Effective management of smear layer ensures adequate clinical success. Use of sodium hypochlorite (NaOCl)/ethylenediaminetetraacetic acid regimen has been the gold standard with limitations. Commercial irrigants incorporate surface modifiers to address these drawbacks. The aim of this study was to evaluate the cytotoxicity of combination regimens on target and nontarget cell lines by trypan blue assay.