Open AccessThe current understanding on langerhans' cells and its role in oral lesions
Author(s) -
Vidyadevi Chandavarkar,
Mithilesh Mishra,
R. Sangeetha,
B R Premalatha
Publication year - 2020
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/ccd.ccd_4_20
Subject(s) - immune system , langerhans cell , oral mucosa , antigen , langerhans cell histiocytosis , immunology , antigen presentation , antigen presenting cell , biology , medicine , pathology , t cell , disease
Description of Langerhans' cells (LCs) as an important antigen-presenting cells responsible for detecting the antigens, recruiting T-cells, and thereby initiating the immune response. An adequate response of the mucosal immune system is essential to protect the mucosa against pathological conditions. Hence, a detailed review was planned about this unique antigen-presenting cell.