Open AccessClinical and radiographic evaluation of citric acid-based nano hydroxyapatite composite graft in the regeneration of intrabony defects - A randomized controlled trial
Author(s) -
Chaurasia Priya Dayashankar,
P C Deepika,
Siddaramaiah Basavarajaiah
Publication year - 2017
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/ccd.ccd_213_17
Subject(s) - regeneration (biology) , citric acid , medicine , dentistry , randomized controlled trial , radiography , composite number , clinical trial , orthodontics , materials science , surgery , chemistry , composite material , biology , pathology , organic chemistry , microbiology and biotechnology
Conventional periodontal therapy with various bone grafts has limited scope and the results are not predictable. To improve their utility, the hybridization of bioceramics and biodegradable polymers has been widely adopted to reform the mechanical properties of bone grafts. One such biodegradable polymer is POC (Poly 1,8 octanediol). Secondly, citric acid is considered as the key material in bone mineralization, which is related to the overall stability, strength and fracture resistance of bone. Hence citric acid is incorporated in a polymer and Nano hydroxyapatite to form a composite graft, for periodontal bone regeneration. This study attempts to evaluate the efficacy of citric acid based Nano-hydroxyapatite composite graft for the treatment of intrabony defects in chronic periodontitis patients over 12 months.