Open AccessAspirin resistance and blood biomarkers in predicting ischemic stroke recurrence: An exploratory study
Author(s) -
Prerana Dash,
Varun Kumar Singh,
Deepa Gautam,
Abhishek Pathak,
Anand Kumar,
Sarita Mishra,
Debabrata Dash,
Vijay Nath Mishra,
Deepika Joshi,
Rameshwar Nath Chaurasia
Publication year - 2022
Publication title -
brain circulation
Language(s) - English
Resource type - Journals
eISSN - 2455-4626
pISSN - 2394-8108
DOI - 10.4103/bc.bc_75_21
Subject(s) - medicine , aspirin , stroke (engine) , etiology , gastroenterology , c reactive protein , diabetes mellitus , cardiology , surgery , inflammation , endocrinology , mechanical engineering , engineering
Recurrent strokes cause greater complications and worse outcomes by adding to the existing neurological deficit. There is the paucity of data on serum markers of inflammation as predictors of recurrent stroke. This study was planned to analyze the clinico-etiological profile of recurrent noncardioembolic ischemic stroke, estimate aspirin resistance among regular aspirin users and evaluate blood biomarkers high-sensitivity C-reactive protein (hsCRP), Tumor necrosis factor-alpha (TNF-α), Lipoprotein-associated phospholipase A 2 (Lp-PLA2) as probable predictors of stroke recurrence.