Open AccessUpdates on the association of brain injury and Alzheimer's disease
Author(s) -
Kara Klomparens,
Yuchuan Ding
Publication year - 2020
Publication title -
brain circulation
Language(s) - English
Resource type - Journals
eISSN - 2455-4626
pISSN - 2394-8108
DOI - 10.4103/bc.bc_18_20
Subject(s) - head trauma , disease , head injury , traumatic brain injury , association (psychology) , medicine , genetic association , neuroscience , psychology , psychiatry , genotype , biology , surgery , single nucleotide polymorphism , genetics , gene , psychotherapist
The purpose of this minireview is to outline the updates made on the association of Alzheimer's disease (AD) and brain injury. A review of the literature on this subject was conducted that included various aspects such as age of onset, severity of head trauma, and genetic influences. The results of this mini-review were that consistent associations of AD risk are seen when the severity of head trauma increases, the lag time decreases and when genetic links are present. Brain injury and AD have a complicated relationship that requires further studies to be fully understood.