Open AccessNecrotizing enterocolitis and congenital heart disease
Author(s) -
Hadi Kashif,
Eyad Abuelgasim,
Nafisa Hussain,
Jessica Luyt,
Amer Harky
Publication year - 2021
Publication title -
annals of pediatric cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 19
eISSN - 0974-2069
pISSN - 0974-5149
DOI - 10.4103/apc.apc_30_21
Subject(s) - medicine , necrotizing enterocolitis , heart disease , pathophysiology , incidence (geometry) , disease , pediatrics , intensive care medicine , population , cardiology , physics , environmental health , optics
Necrotizing enterocolitis (NEC) remains a prominent surgical emergency among infant population, associated with a significant mortality, as well as various subsequent morbidities. Congenital heart disease (CHD) has an increased associated incidence with NEC in infant population. Recent research has provided insight into the pathophysiology of NEC in patients with CHD and how this differs from those without CHD. The deviation from normal circulatory physiology has a suggested association in the pathophysiology of NEC in CHD, which may have implications for the risk factors of NEC in infants with CHD, the effect on outcomes of NEC, and whether alternative approaches to management may need to be considered in comparison to classical NEC. This review aims to highlight studies that provide insight and awareness into the relationship between NEC and CHD, in order that clinicians may direct themselves more clearly toward optimal management for infants in this category.