Open AccessEvaluation of high-dose aspirin elimination in the treatment of Kawasaki disease in the incidence of coronary artery aneurysm
Author(s) -
Farima Sanati,
Mohammad-Mehdi Bagheri,
Shahryar Eslami,
Ali Khalooei
Publication year - 2021
Publication title -
annals of pediatric cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.292
H-Index - 19
eISSN - 0974-2069
pISSN - 0974-5149
DOI - 10.4103/apc.apc_206_20
Subject(s) - medicine , kawasaki disease , aspirin , coronary arteries , incidence (geometry) , artery , aneurysm , coronary artery aneurysm , gastroenterology , cardiology , coronary artery disease , antibody , surgery , immunology , physics , optics
Standard first-step therapy for Kawasaki disease consists of Intravenous immunoglobulin and high dose Aspirin (80-100 mg/kg/day). The standard dose of Intravenous immunoglobulin (2gr/kg) is strongly effective in reducing the risk of coronary arteries abnormalities. So, the proper dose and efficacy of Aspirin to decrease the risk of coronary arteries abnormalities is a controversial issue. In this study, it is tried to assess the result of eliminating high-dose Aspirin in the treatment of the acute phase of Kawasaki and observe the incidence rate of coronary arteries abnormalities when only Intravenous immunoglobulin was administered.