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The expression of matrix metalloproteinase-9 (MMP-9), MMP-13, and tissue inhibitor of metalloproteinases (TIMP-1) in head and neck squamous cell carcinoma (HNSCC) could be a useful predictor of tumour differentiation, nodal metastasis, and invasiveness. We conducted this study to ascertain the correlation between the expression of these markers and differentiation of tumour cells.

annals of maxillofacial surgery

Correlation between the expression of matrix metalloproteinase-9, matrix metalloproteinase-13, tissue inhibitor of metalloproteinases-1, p16 and differentiation of head and neck squamous cell carcinoma: A prospective observational study