Open AccessNeurofibromatosis Type 1 in the Mandible
Author(s) -
Yuka Uchiyama,
Toshiyuki Sumi,
Keisuke Marutani,
Hiroo Takaoka,
Shumei Murakami,
Hiroyasu Kameyama,
Yoshiaki Yura
Publication year - 2018
Publication title -
annals of maxillofacial surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.365
H-Index - 6
ISSN - 2231-0746
DOI - 10.4103/ams.ams_135_17
Subject(s) - medicine , neurofibromatosis , mandible (arthropod mouthpart) , deformity , neural crest , dysplasia , anatomy , iliac crest , neurofibromatosis type i , masticatory force , radiology , orthodontics , pathology , embryo , botany , biology , genus , microbiology and biotechnology
Neurofibromatosis type 1 (NF1) was first described in 1882 as a hamartomatous disorder of neural crest derivation. We present the imaging of a 65-year-old woman with NF1. Computed tomography revealed that there were three major findings presented: skeletal deformity, an area of fat (probably related to mesodermal dysplasia), and benign neoplasm within the masticator space. Moreover, masticatory muscles were hypoplastic.