Open AccessEvaluation of bacterial inactivation in random donor platelets and single-donor apheresis platelets by the INTERCEPT blood system
Author(s) -
Raj Nath Makroo,
Raman Sardana,
Leena Mediratta,
Hena Butta,
Uday Kumar Thakur,
Soma Agrawal,
Mohit Chowdhry,
Satish Kumar,
Sourit Chokroborty
Publication year - 2018
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/ajts.ajts_87_17
Subject(s) - platelet , escherichia coli , medicine , apheresis , contamination , microbiology and biotechnology , staphylococcus aureus , platelet transfusion , bacteria , bacterial growth , sepsis , immunology , biology , biochemistry , ecology , genetics , gene
Blood transfusion of contaminated components is a potential source of sepsis by a wide range of known and unknown pathogens. Collection mechanism and storage conditions of platelets make them vulnerable for bacterial contamination. Several interventions aim to reduce the transfusion of contaminated platelet units; however, data suggest that contaminated platelet transfusion remains very common.