Open AccessPrevalance of Anti-HLA antibodies in parous female blood donors: A pilot study from tertiary care hospital of north india
Author(s) -
A Priyadarsini,
Hari Krishan Dhawan,
Ratti Ram Sharma,
Biman Saikia,
Ranjana Walker Minz
Publication year - 2021
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/ajts.ajts_30_19
Subject(s) - medicine , antibody , human leukocyte antigen , immunology , blood transfusion , tertiary care , antigen
Various studies have implicated that plasma causing transfusion-related acute lung injury is from alloimmunized females. The frequency of sensitization to human leukocyte antigen (HLA) was found to correlate with their parity score. No literature on the prevalence of anti-HLA antibodies in Indian blood donors is available to date. Hence, this pilot study was done to know the frequency of HLA alloimmunization in Indian blood donors.