Open AccessAnti Kpa alloantibody: Development of a rare alloantibody in a non-Hodgkin's lymphoma patient of Indian origin
Author(s) -
Sadhana Mangwana,
Vivek Gangwar
Publication year - 2018
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/ajts.ajts_23_17
Subject(s) - abo blood group system , medicine , antibody , lymphoma , isoantibodies , immunology , immune system , autoantibody , antigen , isoantigens , virology
The Kell blood group system is complex, contains many antigens, highly immunogenic, and potent in triggering immune reactions. Antibodies to Kell blood group system are the most common immune red cell antibodies, following ABO and Rh. However, among the anti-Kell antibodies; anti-Kp a is extremely rare. We report an interesting case of Anti-Kp a in a 59-year-old female patient of Non-Hodgkin's Lymphoma, post radiotherapy, who first developed warm autoantibody and later developed anti-Kp a alloantibody on multiple transfusions.