Open AccessA rare case of hemolytic disease of newborn due to weak D (D unknown) antigen in child
Author(s) -
Nirav Ramesh Dava,
Alok Upadhyaya,
Neha Agarwal,
Akshay Mehta,
Vijaypal Choudhary,
Gourav Goyal
Publication year - 2018
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/ajts.ajts_21_17
Subject(s) - medicine , rare disease , hemolytic disease of the newborn (abo) , disease , antigen , pediatrics , immunology , genetics , pregnancy , fetus , biology
We are reporting a rare case of hemolytic disease of newborn with weak D antigen in child. A 3 rd order male child of G 3 P 3 A 0 mother was admitted at 8 th h of life with jaundice. Blood group of both mother and child were A Rh D negative. Baby's direct coombs test was positive. Weak D antigen was positive in baby. Hematological parameters showed all the signs of ongoing hemolysis, and the bilirubin level was in the zone of exchange transfusion. Exchange transfusion was done. An intravenous immunoglobulin was given to child after that. Mother had a history of first normal healthy male child with O Rh D positive blood group. Second male child expired on 3 rd postnatal day due to bilirubin encephalopathy that had A Rh D negative blood group with positive direct coombs test.