Open AccessCritical analysis of two cases of major crossmatch incompatibility in tertiary care hospital in Delhi
Author(s) -
Vandana Puri,
Garima Sharma,
Aruna Chhikara
Publication year - 2020
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/ajts.ajts_155_17
Subject(s) - medicine , antigen , antibody , blood transfusion , immunology , tertiary care , rh blood group system , sensitization , virology
Rh blood group is one of the most complexes of the human blood groups system. RHD gene encodes the D antigen, and the RHCE encodes the C, c, E, and e antigens. Out of these, Rh D antigen is the most immunogenic while e antigen is the least immunogenic. Rh antibodies are produced in Rh-negative individuals following sensitization which occurs either through pregnancy or during blood transfusion. We hereby report two cases of anti-e antibody, both presenting as major crossmatch incompatibility.