Open AccessHeterogeneity of O blood group in India: Peeping through the window of molecular biology
Author(s) -
Harita Gogri,
Sabita Ray,
Snehal Agrawal,
S. Aruna,
Kanjaksha Ghosh,
Ajit Gorakshakar
Publication year - 2018
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/ajts.ajts_12_17
Subject(s) - abo blood group system , genotyping , genotype , population , polymerase chain reaction , allele , ethnic group , genetics , medicine , gene , biology , environmental health , anthropology , sociology
Molecular genotyping of ABO blood group system has identified more than 60 "O" group alleles based on the single-nucleotide polymorphisms present in the ABO gene. Heterogeneity of O group alleles has been observed in various countries from South America, Europe, Middle East, and Asia. India is a vast country with more than 1300 million population which is divided into various ethnic and tribal groups. However, very little is known about the heterogeneity of O alleles in Indians.