Open AccessAcute respiratory distress syndrome in a neonate due to possible transfusion-related acute lung injury
Author(s) -
Arti Maria,
Saurabh Agarwal,
Anu Sharma
Publication year - 2017
Publication title -
asian journal of transfusion science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.262
H-Index - 22
eISSN - 1998-3565
pISSN - 0973-6247
DOI - 10.4103/ajts.ajts_120_16
Subject(s) - medicine , transfusion related acute lung injury , diffuse alveolar damage , respiratory distress , acute respiratory distress , complication , intensive care medicine , blood transfusion , lung , blood product , pulmonary hemorrhage , anesthesia , surgery , pulmonary edema
Transfusion-related acute lung injury (TRALI) is a potentially life-threatening complication of blood component transfusion. It is relatively underdiagnosed entity in neonates with scant literature. We report a case of TRALI in a preterm neonate developing acute respiratory distress within 6 h of blood product transfusion in the absence of preexisting lung disease. Prompt ventilator and supportive management were instituted. The baby showed clinical and radiological improvement within 12 h; however, he succumbed to death due to acute massive pulmonary hemorrhage 36 h later. Possibility of TRALI should be kept if there is sudden deterioration of lung function after blood transfusion.