Open AccessA study on genetic polymorphism of RET proto-oncogene in Hirschsprung's disease in children
Author(s) -
Madhu Kumari,
Chhanda Das,
Madhumita Mukhopadhyay,
Rishav Dev Patra,
Pinaki Mitra,
Biswanath Mukhopadhyay
Publication year - 2020
Publication title -
african journal of paediatric surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.163
H-Index - 17
eISSN - 0189-6725
pISSN - 0974-5998
DOI - 10.4103/ajps.ajps_69_17
Subject(s) - genotype , odds ratio , medicine , gastroenterology , single nucleotide polymorphism , disease , confidence interval , case control study , hirschsprung's disease , ret proto oncogene , polymorphism (computer science) , genetics , biology , gene , mutation , germline mutation
Hirschsprung's disease (HD) is a genetic disorder with a complex pattern of inheritance. Some single-nucleotide polymorphisms (SNPs) are identified to be associated with the risk of Hirschsprung's Disease (HSCR).