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The maintenance of hemodynamic stability is of pivotal importance in aneurysm surgeries. While administering anesthesia in these patients, the fluctuations in blood pressure may directly affect transmural pressure, thereby precipitating rupture of aneurysm and various other associated complications. We aimed to compare the effects of ketofol with propofol alone when used as an induction and maintenance anesthetic agent during surgical clipping of intracranial aneurysms.

asian journal of neurosurgery

Comparison of ketofol (combination of ketamine and propofol) and propofol anesthesia in aneurysmal clipping surgery: A prospective randomized control trial