Open AccessComparison of ketofol (combination of ketamine and propofol) and propofol anesthesia in aneurysmal clipping surgery: A prospective randomized control trial
Author(s) -
Ajit Bhardwaj,
Nidhi Panda,
Rajeev Chauhan,
Summit Dev Bloria,
Neerja Bharti,
Hemant Bhagat,
Vishwanath Bhaire,
Ankur Luthra,
Rajesh Chhabra,
Shalvi Mahajan
Publication year - 2020
Publication title -
asian journal of neurosurgery
Language(s) - English
Resource type - Journals
ISSN - 1793-5482
DOI - 10.4103/ajns.ajns_346_19
Subject(s) - medicine , propofol , anesthesia , ketamine , hemodynamics , clipping (morphology) , aneurysm , blood pressure , surgery , subarachnoid hemorrhage , anesthetic , philosophy , linguistics
The maintenance of hemodynamic stability is of pivotal importance in aneurysm surgeries. While administering anesthesia in these patients, the fluctuations in blood pressure may directly affect transmural pressure, thereby precipitating rupture of aneurysm and various other associated complications. We aimed to compare the effects of ketofol with propofol alone when used as an induction and maintenance anesthetic agent during surgical clipping of intracranial aneurysms.