Open AccessPredictors of levo-dopa induced dyskinesias in Parkinson's disease
Author(s) -
RT Athulya,
S. Jayakrishnan,
Thomas Iype,
Reeja Rajan,
Paul J Alapatt
Publication year - 2020
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/aian.aian_460_18
Subject(s) - levodopa , dyskinesia , medicine , parkinson's disease , logistic regression , observational study , movement disorders , disease , pediatrics
Levodopa has a superior antiparkinsonian effect than dopamine agonists making it the standard of care for patients with Parkinson's disease (PD). During the initial stages, PD patients show a steady response to levodopa. Response fluctuations and levodopa-induced dyskinesias (LID) develop subsequently. The timing and onset of dyskinesias vary among individuals, and there are very few studies identifying the predictors of dyskinesia in India.