Open AccessMultiple neurologic deficits and cognitive decline in a young woman
Author(s) -
Arunmozhimaran Elavarasi,
Jino George,
Mehar Chand Sharma,
Kalpana Kumari,
Ajay Garg,
Awadh Kishor Pandit,
Abhishek Satapathy,
Vinay Goyal
Publication year - 2019
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/aian.aian_293_19
Subject(s) - medicine , maculopapular rash , pancytopenia , pediatrics , cognitive decline , rash , palsy , dermatology , disease , pathology , dementia , alternative medicine , bone marrow
We present the clinicopathologic conference of a 34-year-old lady with history of facial palsy 14 years ago who developed new deficits of mononeuritis multiplex, maculopapular rash, pancytopenia, splenomegaly, lung involvement and cognitive decline rapidly over three years. Investigations revealed pancytopenia, reversal of albumin globulin ratio, mediastinal adenopathy, ANA positivity, low C3 levels with the CSF being inflammatory and MRI showing extensive hemorrhagic lesions with mass effect. She had a rapidly progressive fatal course over three years with the disease being undiagnosed. This case was presented in the annual meeting of the Indian Academy of Neurology in September 2018.