Open AccessGlioblastoma multiforme associated with arteriovenous malformation: A case report and literature review
Author(s) -
Thara Tunthanathip,
Kanet Kanjanapradit
Publication year - 2020
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/aian.aian_219_18
Subject(s) - medicine , vascularity , arteriovenous malformation , glioblastoma , hemiparesis , magnetic resonance imaging , embolization , radiology , magnetic resonance angiography , glioma , angiography , intracranial arteriovenous malformations , surgical resection , cerebral angiography , cancer research
Although microvascular proliferation can be observed in glioblastoma, obvious vascularity coupled with coexisting cerebral arteriovenous malformation (AVM) is extremely rare. This report is of a rare case of glioblastoma, coexisting with a cerebral AVM. A 20-year-old male presented with progressive right hemiparesis within 1 month. Cranial magnetic resonance imaging revealed a large bleeding tumor with surrounding dilated vessels. Cerebral angiography demonstrated a left frontal AVM with a 1.2 cm nidus. The patient underwent preoperative embolization and radical resection. The coincidence of glioma and AVM was a rare association. However, the concept of hypervascular glioblastoma has been used in different states from different literature reviews; therefore, the role of proangiogenic factors should be addressed.