Open AccessEffect of perioperative use of oral triidothyronine for infants undergoing complex congenital cardiac surgeries under cardiopulmonary bypass: A double-blinded randomised controlled study
Author(s) -
Sujithareddy Karri,
Banashree Mandal,
Bhupesh Kumar,
Goverdandutt Puri,
Shyam Kumar Singh Thingnam,
Hemant Kumar,
Vineetha Unnikrishnan
Publication year - 2022
Publication title -
annals of cardiac anaesthesia/annals of cardiac anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.42
H-Index - 27
eISSN - 0974-5181
pISSN - 0971-9784
DOI - 10.4103/aca.aca_51_22
Subject(s) - medicine , cardiopulmonary bypass , anesthesia , placebo , perioperative , ejection fraction , inotrope , cardiac surgery , cardiac output , hemodynamics , heart failure , alternative medicine , pathology
Thyroid hormone metabolism disrupts after cardiopulmonary bypass both in adults and pediatric patients. This is known as Euthyroid sick syndrome, and it is more evident in pediatric patients who were undergoing complex cardiac surgeries compared to adults. This decrease in serum T3 levels increases the incidence of low cardiac output, requirement of inotropes, prolonged mechanical ventilation, and prolonged intensive care unit (ICU) stay.