Open AccessSuccessful management of hypothermic cardiopulmonary bypass in a malignant hyperthermia susceptible patient
Author(s) -
Shvetank Agarwal,
Kevin C. Graham,
Simon Kigwana,
Manuel R. Castresana
Publication year - 2020
Publication title -
annals of cardiac anaesthesia/annals of cardiac anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.42
H-Index - 27
eISSN - 0974-5181
pISSN - 0971-9784
DOI - 10.4103/aca.aca_245_18
Subject(s) - medicine , cardiopulmonary bypass , malignant hyperthermia , hypothermia , regurgitation (circulation) , anesthetic , anesthesia , bentall procedure , halothane , surgery , ascending aorta , aorta
Malignant hyperthermia (MH) is a potentially lethal reaction in those that are genetically predisposed, frequently triggered by inhaled anesthetics. MH is often difficult to diagnose because it is accompanied by signs and symptoms that are shared with other disorders. The diagnosis is further obscured in cardiac surgical patients, as the signs of MH can be masked by the cardiopulmonary bypass circuit (CPB) and the use of induced hypothermia. In this case-report, we describe the successful anesthetic management of a 65-year-old MH-susceptible female, confirmed via caffeine halothane contracture test, with aortic regurgitation and ascending aortic dilatation who underwent a Bentall procedure. We have also identified certain key measures for the safe anesthetic management of these patients.