Open AccessManagement of perioperative anticoagulation in a patient with antiphospholipid antibody syndrome undergoing cardiac surgery: A case report
Author(s) -
Sanjana A. Malviya,
Yi Deng,
Sayyed O Gilani,
Alec A Hendon,
Melissa Nikolaidis,
Micah S Moseley
Publication year - 2022
Publication title -
annals of cardiac anaesthesia/annals of cardiac anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.42
H-Index - 27
eISSN - 0974-5181
pISSN - 0971-9784
DOI - 10.4103/aca.aca_228_20
Subject(s) - medicine , perioperative , cardiopulmonary bypass , activated clotting time , antiphospholipid syndrome , hematoma , surgery , cardiac surgery , anesthesia , thrombosis
Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB). In this case we present a patient with APLS and Immune Thrombocytopenic Purpura who successfully underwent aortic valve replacement (AVR) with CPB despite recent craniotomy for subdural hematoma evacuation. Anticoagulation for CPB was monitored by targeting an Activated Clotting Time (ACT) that was 2× the upper limit of normal. A multidisciplinary approach was essential in ensuring a safe and successful operation.