Open AccessStatin reload before off-pump coronary artery bypass graft: Effect on biomarker release kinetics
Author(s) -
Atul Kaushik,
Aditya Kapoor,
Surendra Kumar Agarwal,
Shantanu Pande,
Prabhat Tewari,
Gauranga Majumdar,
Archana Sinha,
Shiridhar Kashyap,
Roopali Khanna,
Sudeep Kumar,
Naveen Garg,
Satyendra Tewari,
Pravin K. Goel
Publication year - 2020
Publication title -
annals of cardiac anaesthesia/annals of cardiac anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.42
H-Index - 27
eISSN - 0974-5181
pISSN - 0971-9784
DOI - 10.4103/aca.aca_133_18
Subject(s) - medicine , cardiology , statin , off pump coronary artery bypass , biomarker , artery , coronary artery bypass surgery , coronary artery disease , kinetics , bypass grafting , physics , quantum mechanics , biochemistry , chemistry
Statins confer protection from ischemia/reperfusion through various pathways including pleiotropic mechanisms. Following chronic administration, activation of intrinsic cellular mechanisms causes attenuation of these pleiotropic effects.