Open AccessAdequacy of hemostatic resuscitation improves therapeutic efficacy of recombinant activated factor VII and reduces reexploration rate for bleeding in postoperative cardiac surgery patients with refractory hemorrhage
Author(s) -
Joel Feih,
Janelle Juul,
Joseph Rinka,
Lisa M Baumann Kreuziger,
Paul S. Pagel,
Justin N. Tawil
Publication year - 2019
Publication title -
annals of cardiac anaesthesia/annals of cardiac anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.42
H-Index - 27
eISSN - 0974-5181
pISSN - 0971-9784
DOI - 10.4103/aca.aca_108_18
Subject(s) - medicine , refractory (planetary science) , anesthesia , resuscitation , hemostasis , recombinant factor viia , surgery , odds ratio , cardiac surgery , cardiopulmonary resuscitation , coagulopathy , physics , astrobiology
Excessive bleeding and surgical reexploration are common complications that increase the risk of multi-organ failure and prolonged hospitalization after cardiac surgery. Off-label use of recombinant activated factor VII (rFVIIa) is a recommended treatment for refractory bleeding.