Open AccessAddition of cranberry to proton pump inhibitor-based triple therapy for Helicobacter pylori eradication
Author(s) -
Mohammadreza Seyyedmajidi,
Anahita Ahmadi,
Shahin Hajiebrahimi,
Seyedali Seyedmajidi,
Majid Rajabikashani,
Mona Firoozabadi,
Jamshid Vafaeimanesh
Publication year - 2016
Publication title -
journal of research in pharmacy practice
Language(s) - English
Resource type - Journals
eISSN - 2319-9644
pISSN - 2279-042X
DOI - 10.4103/2279-042x.192462
Subject(s) - lansoprazole , helicobacter pylori , clarithromycin , amoxicillin , medicine , regimen , gastroenterology , breath test , proton pump inhibitor , antibiotics , microbiology and biotechnology , biology
Proton pump inhibitor-based triple therapy with two antibiotics for Helicobacter pylori eradication is widely accepted, but this combination fails in a considerable number of cases. Some studies have shown that cranberry inhibits the adhesion of a wide range of microbial pathogens, including H. pylori . The aim of this study was to assess the effect of cranberry on H. pylori eradication with a standard therapy including lansoprazole, clarithromycin, and amoxicillin (LCA) in patients with peptic ulcer disease (PUD).