Open AccessDifferent doses of intravenous Magnesium sulfate on cardiovascular changes following the laryngoscopy and tracheal intubation: A double-blind randomized controlled trial
Author(s) -
Azim Honarmand,
Mohammadreza Safavi,
Sajad Badiei,
Neda Daftari-Fard
Publication year - 2015
Publication title -
journal of research in pharmacy practice
Language(s) - English
Resource type - Journals
eISSN - 2319-9644
pISSN - 2279-042X
DOI - 10.4103/2279-042x.154365
Subject(s) - medicine , laryngoscopy , anesthesia , intubation , bradycardia , heart rate , tracheal intubation , saline , hemodynamics , tachycardia , blood pressure
Laryngoscopy and intratracheal intubation may cause acute hemodynamic instabilities due to catecholamine release. Magnesium sulfate (MgSO4) prevents catecholamine release and results in bradycardia and vasodilatation, so can be used to diminish complications of laryngoscopy and intubation in doses > 50 mg/kg. The aim of this study was to compare the different doses of MgSO4 used to improve cardiovascular instabilities due to laryngoscopy and intratracheal intubation.