Open AccessA prospective study to compare the clinical efficacy of Tolvaptan with 3% hypertonic saline solution in hospitalized patients having hyponatremia
Author(s) -
Jobin Kunjumon Vilapurathu,
Savitha Rajarajan
Publication year - 2014
Publication title -
journal of research in pharmacy practice
Language(s) - English
Resource type - Journals
eISSN - 2319-9644
pISSN - 2279-042X
DOI - 10.4103/2279-042x.132710
Subject(s) - medicine , tolvaptan , hyponatremia , hypertonic saline , tonicity , saline , clinical trial , prospective cohort study , anesthesia , intensive care medicine
Hyponatremia is one of the most common electrolyte abnormalities in hospitalized patients. The treatment of hyponatremia is controversial as rapid correction of serum sodium can give rise to neurologic disorder and at the same time if not corrected timely, it can lead to brain damage. The aim of this study was to compare the efficacy of Tolvaptan with 3% hypertonic saline solution for the management of hyponatremia in hospitalized patients.