Open AccessNeonatal herpes simplex fulminant hepatitis successfully treated with acyclovir
Author(s) -
Said Abuhasna,
Zuhair Shihab,
Shaikha M Al Niyadi,
Hossam M Tatari,
Amer H Al Jundi,
Khalid Atwa
Publication year - 2012
Publication title -
journal of clinical neonatology/journal of clinical neonatology
Language(s) - English
Resource type - Journals
eISSN - 1658-6093
pISSN - 2249-4847
DOI - 10.4103/2249-4847.96761
Subject(s) - medicine , herpes simplex virus , hsl and hsv , fulminant , fulminant hepatitis , virology , hepatitis , immunology , gastroenterology , virus
Disseminated neonatal herpes simplex virus (HSV) infection is characterized by progressive multiple organ failure and high mortality rates up to 85% for untreated neonates. It can result from infection with either HSV-1 or HSV-2. We report the first known case of disseminated neonatal herpes associated with fulminant liver failure caused by HSV-2 who survived without liver transplant.