Open AccessEvaluation of effects of Bauhinia variegata stem bark extracts against milk-induced eosinophilia in mice
Author(s) -
Ravindra G. Mali,
Avinash S. Dhake
Publication year - 2011
Publication title -
journal of advanced pharmaceutical technology and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.325
H-Index - 33
eISSN - 2231-4040
pISSN - 0976-2094
DOI - 10.4103/2231-4040.82949
Subject(s) - leukocytosis , eosinophilia , traditional medicine , biology , eosinophil , crotalaria , medicine , botany , immunology , asthma
Bauhinia variegata Linn (family: Caesalpiniaceae), popularly known as Rakta Kanchnar, is a medium-sized tree found throughout India. The stem bark of B. variegata (BV) is used traditionally in the treatment of asthma, jaundice, tuberculosis, leprosy, and skin diseases. In the present study, we have investigated the role of aqueous (BVA) and ethanol (BVE) extracts of the plant against milk-induced leukocytosis and eosinophilia in albino mice. The results of the study revealed that pretreatment with both the extracts caused significant reduction in the total leukocyte and eosinophil counts in animals in dose-dependent manner. From these results, it can be concluded that the plant BV is having antieosinophilic activity.