Open AccessEstimation of plasma fibrinogen degradation products in oral submucous fibrosis: A clinico-pathological study
Author(s) -
V Reshma,
AShihab Anwar,
Abdulla Mufeed,
A Roshni
Publication year - 2015
Publication title -
journal of international society of preventive and community dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.476
H-Index - 14
eISSN - 2250-1002
pISSN - 2231-0762
DOI - 10.4103/2231-0762.161760
Subject(s) - oral submucous fibrosis , medicine , fibrinogen , fibrin , gastroenterology , pathological , venous blood , grading (engineering) , fibrosis , oral mucosa , pathology , immunology , civil engineering , engineering
Oral submucous fibrosis (OSF) is a disease of the oral mucosa characterized by excessive accumulation of subepithelial collagen, thereby resulting in severe limitation of mouth opening. In OSF, in response to inflammation, the body produces more fibrinogen and its degradation products. The plasma fibrinogen degradation products (FDP) have been reported to be early indicators of fibrin deposition. The present study was intended to ascertain the role of FDP in OSF.