Open AccessImmunohistochemical profiling of Ameloblastomas using cytokeratin, vimentin, smooth muscle actin, CD34 and S100
Author(s) -
Herald J Sherlin,
Anuja Natesan,
Priya Ram,
Pratibha Ramani,
Chandrasekar Thiruvenkadam
Publication year - 2013
Publication title -
annals of maxillofacial surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.365
H-Index - 6
ISSN - 2231-0746
DOI - 10.4103/2231-0746.110084
Subject(s) - vimentin , cytokeratin , pathology , immunohistochemistry , histogenesis , cd34 , ameloblastoma , medicine , histopathology , connective tissue , intermediate filament , keratin 7 , anatomy , biology , cell , cytoskeleton , stem cell , maxilla , genetics
Ameloblastoma is characterized as a slow growing, non-metastatic and a locally invasive tumor with a high risk of recurrence. Immunohistochemical evaluation of ameloblastomas using epithelial and connective tissue specific markers help in studying the histogenesis and assessing the biological behavior. The aim of the study was to study the expression patterns of cytokeratin, vimentin, smooth muscle actin (SMA), S100 and CD34 in ameloblastomas.