Open AccessAzithromycin novel drug delivery system for ocular application
Author(s) -
Ritu Gilhotra,
Kalpagpal,
Dith Mishra
Publication year - 2011
Publication title -
international journal of pharmaceutical investigation
Language(s) - Danish
Resource type - Journals
eISSN - 2230-973X
pISSN - 2230-9713
DOI - 10.4103/2230-973x.76725
Subject(s) - bioadhesive , mucoadhesion , swelling , drug delivery , pharmacology , drug , azithromycin , biomedical engineering , chemistry , materials science , medicine , antibiotics , nanotechnology , biochemistry , composite material
Azithromycin (AZT) is a macrolide antibiotic derived from and similar in structure to erythromycin. Oral administration of AZT is effective for the treatment of trachoma; however, topical formulations are difficult to develop because of the drug's hydrophobicity. The aim of this study is to formulate a novel topical ophthalmic delivery system of AZT.