Open AccessFabrication and in vitro evaluation of mucoadhesive ondansetron hydrochloride beads for the management of emesis in chemotherapy
Author(s) -
Raj Kaur Malik,
Prashant Malik,
Neha Gulati,
Upendra Nagaich
Publication year - 2013
Publication title -
international journal of pharmaceutical investigation
Language(s) - English
Resource type - Journals
eISSN - 2230-973X
pISSN - 2230-9713
DOI - 10.4103/2230-973x.108962
Subject(s) - ondansetron , pharmacology , antiemetic , materials science , particle size , chromatography , chemistry , biomedical engineering , medicine , anesthesia , vomiting
Mucoadhesive beads were fabricated and evaluated for controlled release of an antiemetic drug 'Ondansetron Hydrochloride'. Ondansetron hydrochloride is a serotonin 5-HT3 receptor antagonist mainly used for the treatment of emesis, which occurs as a side effect of chemotherapy.