Open AccessEffect of ethanolic extract of Cryptolepis sanguinolenta stem on in vivo and in vitro glucose absorption and transport: Mechanism of its antidiabetic activity
Author(s) -
AF Ajayi,
R.E. Akhigbe,
O. J. Adewumi,
LO Okeleji,
KB Mujaidu,
Samuel Babafemi Olaleye
Publication year - 2012
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.94265
Subject(s) - diabetes mellitus , medicine , triglyceride , in vivo , pharmacology , traditional medicine , cholesterol , biology , endocrinology , microbiology and biotechnology
Extracts from various morphological parts of Cryptolepis sanguinolenta are widely used traditionally in folklore medicine in many parts of the world for the management, control, and/or treatment of a plethora of human ailments, including diabetes mellitus. In order to scientifically appraise some of the ethnomedical uses of Cryptolepis sanguinolenta, the present study was undertaken to investigate its influence at varying doses on intestinal glucose absorption and transport in relation to its hypoglycemic and hypolipidemic effects in rat experimental paradigms.